The efficacy of three mycotoxin adsorbents to alleviate T-2 toxins - induced toxicity in broiler chickens

 T-2 Toxin is one of the most harmful mycotoxin produced by Fusarium Spp. The present study was carried to monitor the effects of this toxin on some hematological and biochemical parameters. Three anti-mycotoxin products as adsorbents were examined including (DMSO)] Dimethyl sulfoxid, Mycosorb and Zeolite checked to study their combating activities against feed experimentally contaminated with T-2 toxin in dose 1 mg/Kg .Eighty of three day old unsexed broiler chicks were acclimated and randomly divided into Eight experimental groups (10 broiler per group) Group T1 , T2 ,T3 , were fed a basal diet supplemented with 10 ml / kg of 7% (DMSO ) Dimethyl sulfoxide , 1 gm /kg Mycosorb and 1 gm /kg Zeolite respectively . T4 was fed ration supplemented with 1mg /kg T- 2 toxin .Groups T 5 , T 6 , T7 were fed T -2 toxin contaminated diet with ( 1mg /kg ) the feed were supplemented with 10 ml / kg of 7% (DMSO ) Dimethyl sulfoxid , 1 gm /kg Mycosorb and 1 gm /kg Zeolite respectively . Group T 8 represented the negative control fed on balanced died without any additives At the end of experiment birds were scarified and blood was collected on anticoagulant for hematological parameters and without anticoagulant for serum separation ad biochemical parameters .The total erythrocytes count, Hemoglobin content and total Leukocyte count were significantly decreased after T-2 toxin exposure for 6 weeks. Administration of T-2 toxin led to significant increase in serum Alanine aminotransferase, Aspartate transferase Lactate dehydrogenase, Uric acid, Creatinine and glucose . T-2 toxin produced significant decrease in serum protein, albumin, globulin, cholesterol, triglyceride, calcium, phosphorus and magnesium. Supplementation with Mycosorb .Zeolite significantly improved the hematological and biochemical parameters.