Biochemical and antibacterial activity of Jojoba Oil ‘Simmondsia chinensis’ in rats

Al-Ghamdi, Ahmed K.; Sobhy, Hanan; Elkholy, Thanaa A.

doi:10.21608/ejceh.2020.238161

Biochemical and antibacterial activity of Jojoba Oil ‘Simmondsia chinensis’ in rats

Document Type : Scientific and Research

Authors

¹ Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, P.O. Box 80200, Jeddah 21589, Saudi Arabia

² Head of Biochemistry, Toxicology and Food deficiency Dep, AHRI, Cairo, Egypt

³ AlAzhar University – Egypt- Cairo

10.21608/ejceh.2020.238161

Abstract

This study has evaluated the antibacterial effect of Jojoba oil (J.O) in vivo againstStaphylococcus aureus. One hundred mature male Sprague Dawley rats were divided into four groups, including the control groups and the groups treated with J.O. as part of the diet mixture (2.5% of total body weight). Our findings suggest a significant increase in body weight gain (94.0 ±5.404 g for J.O treated rats in comparison to 72.0 ±3.077 g for untreated rats), final body weight (232.0 ±7.277 g for J.O treated rats in comparison to 220.8 ±9.71 g for untreated rats), and internal organs (0.31±0.03 g, 0.802±0.017 g and 28162±8888g for spleen, kidney and liver respectively in J.O treated rats in comparison to 0.268±0.052 , 28218±28786g and 3.708±0.125 g for spleen, kidney and liver respectively in untreated rats). On the other hand, rats infected with S. aureus and fed by ration mixed with J.O. showed insignificant increase in all studied parameters. Average body weight gain was 74.8±3.673 g and internal organs weight were 282..±288.8 ,28288±28886and 4.124±0.275 g for kidney, spleen and liver respectively. The positive control group showed acute septicemia. Blood samples were taken from diverse groups and were used for bacteriological tests and radial immune diffusion tests. Results have revealed that S. aureus was in pure form and identified biochemically.

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