Study of the effect of grape seed extract on the harmful effects of Monosodium Glutamate on chicken embryo Development

Document Type : Scientific and Research

Author

Biology Department, College of Science, King Abdul-Aziz University, Jeddah, Saudi Arabia

Abstract

Monosodium Glutamate (MSG) is used in the food industry as a flavor enhancer added to thousands of food.Several studies have proven the damage caused by MSG on laboratory animals. Therefore, this study aims to study the effectiveness of grape seed extract(GSE) in mitigating MSG damage on chicken embryos, as part of the solutions provided in the event of the long term use of MSG and its accumulation in the body Human. In this study, we use 300 eggs were divided into six groups which are the control, MSG Group, GSE group, MSG+GSE , GSE than MSG and MSG than GSE. We are studying the effect of experimental materials in the fetal development during the following ages (7, 10, 12, 14, 16) day. The results showed that the treatment of embryos with MSG dose (0.1 ml) caused of the affect growth retardation, congenital malformations and Significant decrease in the weight and height of the fetuses and after the treatment of the fetus GSE was noted to reduce the damage. Grape seed extract has a curative effect in reducing the damages of mono-glutamate sodium on the development of chicken embryos. 

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Egyptian Journal of Chemistry and Environmental Health
Volume 6, Issue 2
November 2020
Pages 1-12

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