Ameliorative effect of Celery( Apium gravealens) and Sweet Marjoram (Origanium marjoram) on some biochemical parameters of diabetic male rats

Document Type : Scientific and Research

Authors

Biochemistry, Toxicology And Feed deficiency Depart. Animal Health Research Institute,Dokki.

Abstract

The goal of this study was to determine some biochemical activities of two medicinal plants Celery( Apium gravealens) and Sweet marjoram (Origanium marjoram) on normal and diabetic rats for 30 successive days . Twenty mature rats of an average body weight of (150-180 gm ) were divided into 4 groups 5 rats each.(G1) control ,(G2) diabetic control group injected intrapretonial by alloxan in a dose 150 mg/kg b.wt .(G3)diabetic rats fed on basal diet mixed with 1% dried Celery( Apium gravealens),(G4) diabetic rats fed on basal diet mixed with 1% dried SweetMarjoram (Origanium marjoram) .At the end of the experiment ,serum blood samples were collected to determine some biochemical parameters , some oxidative markers and relative organs weights . Rats were sacrified and organs were weighed to determine relative organs weight .Results revealed that there were a significant decrease of serum levels of AST,ALT,ALP,cholesterol, triglyceride ,urea and glucose as well as MDA than diabetic control groups at P<0.05.On the otherhand our result found no effect on albumin ,globulin and A/G ratio while catalase enzyme activity showed a significant increase than control diabetic one . the relative organs weight in (G3)and (G4) returned toward normal values.Conclusively ,fed Celery or Sweet marjoram to diets of diabetic male had a beneficial practical tool to minimize the effect of diabetes without any adverse effect on metabolic parameters and organs weight of rats. 

Main Subjects

Egyptian Journal of Chemistry and Environmental Health
Volume 4, Issue 2
November 2018
Pages 1-12

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